LGC übernimmt Axolabs GmbH

LGC acquires Axolabs and invests in GMP manufacturing capacity for therapeutic nucleic acids

LGC announced that it has acquired Axolabs, a leading Contract Research, Development and Manufacturing Organisation, specialising in the development of therapeutic nucleic acids  (TNAs).

LGC also announced a major investment at its Biosearch subsidiary in Petaluma, California, USA to expand its GMP oligonucleotide manufacturing capacity to provide TNA synthesis to the 1kg scale in support of early stage clinical trials.

The acquisition and investment in GMP capacity position LGC as a world leading solutions provider for TNAs and strengthen its existing analytical and bioanalytical drug development service offering. Customers will benefit from integrated analytical and manufacturing solutions spanning lead discovery through to the clinic and beyond.

Dr David Griffiths, Managing Director of LGC’s LMS division, said: “We are delighted to be welcoming Axolabs to LGC. With more than 16 years’ experience in the therapeutic nucleic acid market Axolabs enjoys a strong reputation for scientific excellence, quality and reliability – attributes that match LGC’s.  Axolabs’ in-depth know-how in the TNA drug development field complements LGC’s capabilities in GMP oligo manufacture, CMC analytical and bioanalytical services and we look forward to working together with the Axolabs team and its customers.”

Dr Hans-Peter Vornlocher, Managing Director Research of Axolabs, said: “It is clear that LGC shares our passion for delivering the highest quality science and service for our customers.  This transition of ownership allows us to continue to invest in our team and facilities at Kulmbach. Combining Axolabs’ pre-clinical expertise and LGC’s GMP manufacturing capabilities allows us to support our clients further along the drug development pathway. Moreover, the access to LGC’s leading science and international reach  enables us offer a broader set of solutions for our customers.”

Based in Kulmbach, Southern Germany, Axolabs employs 60 people and delivers integrated research solutions for TNAs, covering in-silico design, synthesis, analytics, bioanalytics, biology, pharmacology and consulting services.  Axolabs’ expertise spans a wide range of TNA modalities including antisense oligos, siRNAs, immunostimulatory oligos, aptamers, microRNAs and microRNA mimics, synthetic mRNAs and guide RNAs for CRISPR applications.  Axolabs’ management team will remain with the business following the transaction.

About LGC

LGC is an international life sciences measurement and testing company with leading positions in growing markets. LGC provides a range of measurement products and services which underpin the safety, health and security of the public, including reference materials and proficiency testing, genomics reagents and instrumentation, and expert sample analysis and interpretation. LGC serves customers across a number of end markets including Pharmaceuticals, Agricultural Biotechnology, Diagnostics, Food, Environment, Government and Academia.

LGC’s headquarters are in London and the company employs over 2,600 people, operating out of 22 countriesworldwide. Its operations are extensively accredited to international quality standards such as ISO/IEC 17025,ISO 13485, ISO 9001, GMP, GLP and ISO Guide 34. With a history dating back to 1842, LGC has been home to the UK Government Chemist for more than 100 yearsand is the UK National Measurement Laboratory and Designated Institute for chemical and bio measurement.LGC was privatised in 1996 and is now owned by funds affiliated with KKR. For more information, please visit www.lgcgroup.com

About Axolabs

Axolabs is a leading Contract Research, Development and Manufacturing Organisation, focused on the discovery and pre-clinical phases of drug development in the field of oligonucleotide therapeutic and other nucleic acid medicines. The company was founded in 2000 as Ribopharma, a spin-out from the University of Bayreuth, as the world’s first RNAi therapeutics company. It subsequently became part of Alnylam and then Roche and was the subject of a management buy-out in late 2011. For more information, please visit www.axolabs.com

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